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2017
"A-to-I RNA editing in the earliest-diverging eumetazoan phyla".
Porath HT, Schaffer A, Kaniewska P, Alon S, Eisenberg E, Rosenthal J, Levanon EY*, Levy O*
Mol Biol Evol. 2017 (in press)
"Trade-off between Transcriptome Plasticity and Genome Evolution in Cephalopods".
Liscovitch-Brauer N, Alon S, Porath HT, Elstein B,Unger R, Ziv T, Admon A, Levanon EY, ,Rosenthal, JJC,* Eisenberg E*.
Cell 2017, 169,191-202
"Abnormalities in A-to-I RNA editing patterns in CNS injuries correlate with dynamic changes in cell type composition".
Gal-Mark N, Shallev L, Sweetat S, Barak M, Billy Li J, Levanon EY, Eisenberg E, Behar O.
Scientific Reports 2017, 7:43421
"Control and automation of multilayered integrated microfluidic device fabrication".
Kipper S, Frolov L, Guy O, Pellach M, Glick Y, Malichi A, Knisbacher BA, Barbiro-Michaely E, Avrahami D, Yavets-Chen Y, Levanon EY, Gerber D.
Lab on a Chip. 2017, 17(3):557-566.
2016
"Extensive RNA editing and splicing increase immune self-representation diversity in medullary thymic epithelial cells".
Danan-Gotthold M, Guyon C, Giraud M, Levanon EY*, Abramson J*
Genome Biology. 2016 Oct 24;17(1):219
"Clustered mutations in hominid genome evolution are consistent with APOBEC3G enzymatic activity".
Pinto Y*, Gabay O*, Arbiza L, Sams AJ, Keinan A*, Levanon EY*.
Genome Research 2016

Highlighted in Science

"DNA Editing of LTR Retrotransposons Reveals the Impact of APOBECs on Vertebrate Genomes".
Knisbacher BA, Levanon EY
Mol Biol Evol. . pii: msv239.
"Transcriptome, genetic editing, and microRNA divergence substantiate sympatric speciation of blind mole rat, Spalax".
Li K, Wang L, Knisbacher BA, Xu Q, Levanon EY, Wang H, Frenkel-Morgenstern M, Tagore S, Fang X, Bazak L, Buchumenski I, Zhao Y, Lövy M, Li X, Han L, Frenkel Z, Beiles A, Cao YB, Wang ZL, Nevo E.
PNAS 2016 Jul 5;113(27):7584-9.
"Reduced levels of protein recoding by A-to-I RNA editing in Alzheimer's disease.".
Khermesh K, D'Erchia AM, Barak M, Annese A, Wachtel C, Levanon EY, Picardi E, Eisenberg E
RNA doi: 10.1261/rna.054627.115.
"APOBECs: A Genomic Preserver and Transformer.".
Knisbacher BA, Gerber D, Levanon EY
Trends Genet. 2016 Jan;32(1):16-28.
"Activation-Induced Cytidine Deaminase Links Ovulation-Induced Inflammation and Serous Carcinogenesis".
Sapoznik S, Bahar-Shany K, Brand H, Pinto Y, Gabay O, Glick-Saar E, Dor C, Zadok O, Barshack I, Zundelevich A, Gal-Yam EN, Yung Y, Hourvitz A, Korach J, Beiner M, Jacob J, Levanon EY, Barak M, Aviel-Ronen S, Levanon K
Neoplasia. 2016 Feb;18(2):90-9
"A novel homozygous splice site mutation in NALCN identified in siblings with cachexia, strabismus, severe intellectual disability, epilepsy and abnormal respiratory rhythm".
Gal M, Magen D, Zahran Y, Eran A, Khayat M, Gafni C, Levanon EY, Mandel H, Ravidi S
Eur J Med Genet. 2016 (4):204-209.
"Expanding preconception carrier screening for the Jewish population using high throughput microfluidics technology and next generation sequencing".
Gal M, Khermesh K, Barak M, Lin M, Lahat H, Reznik-Wolf H, Lin M, Pras E and Levanon EY
BMC Medical Genomics 2016, doi:10.1186/s12920-016-0184-7
2015
"Elevated RNA editing activity is a major contributor to transcriptomic diversity in tumors"
Paz-Yaacov N, Bazak L, Buchumenski I, Porath HT, Danan-Gotthold M, Knisbacher BA, Eisenberg E, Levanon EY.
Cell Reports . 2015 Oct 13;13(2):267-76

Featured on Nature Reviews Cancer and highlighted in Breakthroughs of the Year by Science Signaling

"Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish.".
Shamay-Ramot A, Khermesh K, Porath HT, Barak M, Pinto Y, Wachtel C, Zilberberg A, LererGoldshtein T, Efroni S, Levanon EY, Appelbaum L
PLoS Genet 2015, 11(12):e1005702.
"DNA and RNA editing of retrotransposons accelerate mammalian genome evolution.".
Knisbacher BA, Levanon EY
Ann N Y Acad Sci. 2015 Feb 26.
“The majority of transcripts in the squid nervous system are extensively recoded by A-to-I RNA editing”.
Alon S, Garrett SC, Levanon EY, Olson S, Graveley BR, Rosenthal JJ, Eisenberg E.
Elife. 2015 Jan 8;4.

Featured on Science

“m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation”
Geula S, Moshitch-Moshkovitz S, Dominissini D, Mansour AA, Kol N, Salmon-Divon M, Hershkovitz V, Peer E, Mor N, Manor YS, Ben-Haim MS, Eyal E, Yunger S, Pinto Y, Jaitin DA, Viukov S, Rais Y, Krupalnik V, Chomsky E, Zerbib M, Maza I, Rechavi Y, Massarwa R, Hanna S, Amit I, Levanon EY, Amariglio N, Stern Ginossar N, Novershtern N, Rechavi G, Hanna JH
Science. 2015 Jan 1.
“Analysis of intron sequences reveals hallmarks of circular RNA biogenesis in animals”
Ivanov A, Memczak S, Wyler E, Torti F, Porath HT, Orejuela MR, Piechotta M, Levanon EY, Landthaler M, Dieterich C, Rajewsky N. Analysis of intron sequences
Cell Reports . 2015 Jan13;10(2):170-7
“Does RNA editing compensate for Alu invasion of the primate genome?”
Levanon EY, Eisenberg E.
Bioessays. 2015 Feb;37(2):175-81.
“Identification of recurrent regulated alternative splicing events across human solid tumors.”
Danan-Gotthold M, Golan-Gerstl R, Eisenberg E, Meir K, Karni R, Levanon EY.
Nucleic Acids Res. 2015 May 26;43(10):5130-44
2014
"Novel mutation in TSPAN12 leads to autosomal recessive inheritance of congenital vitreoretinal disease with intra-familial phenotypic variability"
Gal M, Levanon EY, Hujeirat Y, Khayat M, Pe'er J, Shalev S.
Am J Med Genet A. 2014 (12):2996-3002.
“A genome-wide map of hyper-edited RNA reveals numerous new sites”
Porath HT, Carmi S, Levanon EY.
Nature Communications. 2014 Aug 27;5:4726.
“Characterizing of functional human coding RNA editing from evolutionary, structural, and dynamic perspectives”
Solomon O, Bazak L, Levanon EY, Amariglio N, Unger R, Rechavi G, Eyal E.
Proteins. 2014 Nov;82(11):3117-31.
“Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax”
Fang X, Nevo E, Han L, Levanon EY, Zhao J, Avivi A, Larkin D, Jiang X, Feranchuk S, Zhu Y, Fishman A, Feng Y, Sher N, Xiong Z, Hankeln T, Huang Z, Gorbunova V, Zhang L, Zhao W, Wildman DE, Xiong Y, Gudkov A, Zheng Q, Rechavi G, Liu S, Bazak L, Chen J, Knisbacher BA, Lu Y, Shams I, Gajda K, Farré M, Kim J, Lewin HA, Ma J, Band M, Bicker A, Kranz A, Mattheus T, Schmidt H, Seluanov A, Azpurua J, McGowen MR, Ben Jacob E, Li K, Peng S, Zhu X, Liao X, Li S, Krogh A, Zhou X, Brodsky L, Wang J
Nature Communications . 2014 Jun 3;5:3966.
“Genome-wide analysis of Alu editability“
Bazak L, Levanon EY, Eisenberg E.
Nucleic Acids Res. 2014 Jun;42(11):6876-84.
“Mammalian conserved ADAR targets comprise only a small fragment of the human editosome”
Pinto Y, Cohen HY, Levanon EY
Genome Biology 2014 Jan 7;15(1):R5.
“A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes”
Bazak L, Haviv A, Barak M, Jacob-Hirsch J, Deng P, Zhang R, Isaacs FJ, Rechavi G, Li JB, Eisenberg E, Levanon EY
Genome Research 2014 Mar;24(3):365-76.
“Positive correlation between ADAR expression and its targets suggests a complex regulation mediated by RNA editing in the human brain.”
Liscovitch N, Bazak L, Levanon EY, Chechik G.
RNA Biol. 2014; 11:1448-57.
2013
"Human housekeeping genes, revisited."
Eisenberg E, Levanon EY.
pdf icon   Trends in Genetics. 2013 Oct;29(10):569-74.
Also available on:
Trends in Genetics
"Differential inhibition of LINE1 and LINE2 retrotransposition by vertebrate AID/APOBEC proteins."
Lindi NA, Budi MK, Petan T, Knisbacher BA, Levanon EY, Lov In N.
pdf icon   Retrovirology. 2013 Dec 17;10(1):156.
Also available on:
Retrovirology
2012
"Activity dependent A-to-I RNA editing in rat cortical neurons"
Neville E. Sanjana*, Erez Y. Levanon**, Emily A. Hueske, Jessica M. Ambrose, and Jin Billy Li
pdf icon   June 19, 2012, doi: 10.1534/genetics.112.141200
Also available on:
Genetics
2011
"Identification of Widespread Ultra-Edited Human RNAs"
Shai Carmi, Itamar Borukhov, Erez Y. Levanon
pdf icon   PLoS Genet 7(10): e1002317. doi:10.1371/journal.pgen.1002317
Also available on:
PLoS Genetics
"Large-scale DNA editing of retrotransposons accelerates mammalian genome evolution"
Shai Carmi, George M. Church & Erez Y. Levanon
pdf icon   Nature Communicationsin 2011 Nov 1;2:519
Also available on:
Nature
2010
“Adenosine-to-inosine RNA editing shapes transcriptome diversity in primates”
Nurit Paz-Yaacov, Erez Y. Levanon, Eviatar Nevo, Yaron Kinar, Alon Harmelin, Jasmine Jacob-Hirsch, Ninette Amariglio, Eli Eisenberg, and Gideon Rechavi.
pdf icon   PNAS 107, 12174-12179 (2010)
“Age-related gene-specific changes of A-to-I mRNA editing in the human brain”
A. Nicholas , J.P.deMagalhaes , Y.Kraytsberg , E.K.Richfield , E.Y.Levanon , K.Khrapko
pdf icon   Mechanisms of ageing and development 2010 Jun;131(6):445-7
“A Survey of Genomic Traces Reveals a Common Sequencing Error, RNA Editing, and DNA Editing”
Alexander Wait Zaranek, Erez Y. Levanon, Tomer Zecharia, Tom Clegg, George M. Church
pdf icon   PLoS Genetics 6(5): e1000954. doi:10.1371/journal.pgen.1000954
Featured on Nature and Nature methods
“Consistent levels of A-to-I RNA editing across individuals in coding sequences and nonconserved Alu repeats”
Shoshana Greenberger†, Erez Y Levanon†, Nurit Paz-Yaacov, Aviv Barzilai, Michal Safran, Sivan Osenberg,Ninette Amariglio, Gideon Rechavi, Eli Eisenberg
pdf icon   BMC Genomics 2010, 11:608
“Sequence based identification of RNA editing sites”
Eli Eisenberg, Jin Billy Li, and Erez Y. Levanon
pdf icon   RNA Biology 7:2, 1-5; March/April 2010
2009
“Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing”
Jin Billy Li, Erez Y. Levanon, Jung-Ki Yoon, John Aach,Bin Xie, Emily LeProust, Kun Zhang, Yuan Gao, and George M. Church
pdf icon   Science 324, 1210-1213 (2009)
Featured on Nature Reviews Genetics
“Evidence for large diversity in the human transcriptome created by Alu RNA editing”
Michal Barak, Erez Y. Levanon, Eli Eisenberg, Nurit Paz, Gideon Rechavi, George M. Church and Ramit Mehr
pdf icon   Nucleic Acids Research, 2009, 1–11
“Efficiency of complex production in changing environment”
Shai Carmi, Erez Y Levanon and Eli Eisenberg
pdf icon   BMC Systems Biology 2009, 3:3
2008
“Intronic Alus Influence Alternative Splicing”
Galit Lev-Maor., Oren Ram., Eddo Kim., Noa Sela., Amir Goren, Erez Y. Levanon, Gil Ast
pdf icon   PLoS Genetics 4(9): e1000204
2007
“Altered adenosine-to-inosine RNA editing in human cancer”
Nurit Paz, Erez Y. Levanon, Ninette Amariglio, et al.
pdf icon   Genome Research 2007 17: 1586-1595
“RNA-editing-mediated exon evolution”
Galit Lev-Maor, Rotem Sorek, Erez Y Levanon, Nurit Paz,Eli Eisenberg and Gil Ast
pdf icon   Genome Biology 2007, 8:R29
2006
“Algorithmic approaches for identification of RNA editing sites”
Erez Y. Levanon and Eli Eisenberg
pdf icon   RIEFINGS IN FUNCTIONAL GENOMICS AND PROTEOMICS 2006
“Connectivity and expression in protein networks: Proteins in a complex are uniformly expressed”
Shai Carmi, Erez Y. Levanon, Shlomo Havlin, and Eli Eisenberg
pdf icon   PHYSICAL REVIEW E 73, 031909
“RNA editing level in the mouse is determined by the genomic repeat repertoire”
Yossef Neeman, Erez Y. Levanon, Michael F. Jantsch, et al.
pdf icon   RNA 2006 12: 1802-1809
2005
“Evidence for abundant transcription of non-coding regions in the Saccharomyces cerevisiae genome”
Moshe Havilio, Erez Y Levanon, Galia Lerman, Martin Kupiec and Eli Eisenberg
pdf icon   BMC Genomics 2005, 6:93
“Evolutionarily conserved human targets of adenosine to inosine RNA editing”
Erez Y. Levanon, Martina Hallegger, Yaron Kinar, Ronen Shemesh, Kristina Djinovic-Carugo, Gideon Rechavi, Michael F. Jantsch and Eli Eisenberg
pdf icon   Nucleic Acids Research, 2005, Vol. 33, No. 4
“From genome to antivirals: SARS as test tube”
Yossef Kliger,Erez Y.Levanon and Doron Gerber
pdf icon   “Drug Discovery Today” volume 10, number 5 march 2005
“Identification of RNA editing sites in the SNP database”
Eli Eisenberg, Konstantin Adamsky, Lital Cohen, Ninette Amariglio,Abraham Hirshberg, Gideon Rechavi and Erez Y. Levanon
pdf icon   Nucleic Acids Research, 2005, Vol. 33, No. 14
“Is abundant A-to-I RNA editing primate-specific?”
Eli Eisenberg, Sergey Nemzer, Yaron Kinar, Rotem Sorek, Gideon Rechavi and Erez Y. Levanon
pdf icon   Trends in Genetics Vol.21 No.2 February 2005
“Is there any sense in antisense editing?”
Yossef Neeman, Dvir Dahary, Erez Y. Levanon, Rotem Sorek and Eli Eisenberg
pdf icon   Trends in Genetics Vol.21 No.10 October 2005
“Letter from the editor: adenosine-to-inosine RNA editing in Alu repeats in the human genome”
Keren Levanon, Eli Eisenberg, Gideon Rechavi & Erez Y. Levanon
pdf icon   EMBO reports (2005) 6, 831–835
2004
“Evolution of multicellularity in Metazoa: comparative analysis of the subcellular localization of proteins in Saccharomyces, Drosophila and Caenorhabditis”
Einat Hazkani-Covo, Erez Y. Levanon, Galit Rotman, Dan Graur, Amit Novik
pdf icon   Cell Biology International 28 (2004) 171–178
“Systematic identification of abundant A-to-I editing sites in the human transcriptome”
Erez Y Levanon, Eli Eisenberg, Rodrigo Yelin, Sergey Nemzer,Martina Hallegger, Ronen Shemesh, Zipora Y Fligelman, Avi Shoshan, Sarah R Pollock, Dan Sztybel,Moshe Olshansky, Gideon Rechavi & Michael F Jantsch
pdf icon   NATURE BIOTECHNOLOGY VOLUME 22 NUMBER 8 AUGUST 2004
Featured on Nature Biotechnology
2003
“Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy”
Yossef Kliger and Erez Y Levanon
pdf icon   BMC Microbiology 2003, 3:20
“Preferential Attachment in the Protein Network Evolution”
Eli Eisenberg and Erez Y. Levanon
pdf icon   Physical Review Letters . 2003 Sep 26;91(13):138701
“Human housekeeping genes are compact”
Eli Eisenberg and Erez Y. Levanon
pdf icon   Trends in Genetics Vol.19 No.7 July 2003
“The importance of alternative splicing in the drug discovery process”
Erez Y. Levanon and Rotem Sorek
pdf icon   Targets Vol 2, No 3 June 2003
“Widespread occurrence of antisense transcription in the human genome”
Roderigo Yelin, Dvir Dahary, Rotem Sorek, Erez Y. Levanon, Orly Goldsein, Avi Shoshan, Alex Diber, Sharon Biton, Rami Tamir, Rami Khsravi, Sergey Nemzer, Elhanan Pinner, Shira Walach, Jeanne Bernstein, Kinneret Savitsky, and Galit Rotman
pdf icon   Nature Biotechnology, 2003 Apr;21(4):379-86